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Hyper IgE : ウィキペディア英語版
Hyperimmunoglobulin E syndrome

Hyperimmunoglobulinemia E syndrome (HIES), also called Job's syndrome〔 and Buckley syndrome,〔 is a heterogeneous group of immune disorders.
==Presentation==
It is characterized by recurrent "cold" staphylococcal infections, unusual eczema-like skin rashes, severe lung infections that result in pneumatoceles (balloon-like lesions that may be filled with air or pus or scar tissue) and very high concentrations of the serum antibody IgE. Inheritance can be autosomal dominant or autosomal recessive. Many patients with autosomal dominant hyper IgE syndrome fail to lose their primary teeth and have two sets of teeth simultaneously.
A common mnemonic used to remember the symptoms is FATED: coarse or leonine facies, cold staph abscesses, retained primary teeth, increased IgE, and dermatologic problems ().

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Hyperimmunoglobulin E syndrome」の詳細全文を読む



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